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Jennifer L Clarke Selected Research

vorasidenib

1/2021Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial.

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Jennifer L Clarke Research Topics

Disease

33Neoplasms (Cancer)
02/2022 - 04/2006
21Glioblastoma (Glioblastoma Multiforme)
10/2022 - 08/2009
18Glioma (Gliomas)
08/2022 - 09/2014
4Astrocytoma (Pilocytic Astrocytoma)
01/2022 - 01/2015
3Brain Neoplasms (Brain Tumor)
01/2019 - 01/2012
3Disease Progression
01/2017 - 05/2009
3Neoplasm Metastasis (Metastasis)
02/2012 - 09/2010
2Neurocytoma
01/2020 - 01/2016
2Hypoxia (Hypoxemia)
10/2016 - 01/2015
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2012 - 12/2011
2Lung Neoplasms (Lung Cancer)
12/2011 - 09/2010
1Oligodendroglioma
08/2022
1Barrett Esophagus (Barrett's Esophagus)
02/2022
1Esophageal Neoplasms (Esophageal Cancer)
02/2022
1Aneuploidy (Aneuploid)
01/2022
1Celiac Disease (Celiac Sprue)
12/2021
1Spinal Injuries (Spinal Injury)
08/2021
1Body Weight (Weight, Body)
04/2021
1Pulmonary Hypertension
04/2021
1Liver Diseases (Liver Disease)
04/2021
1Pulmonary Embolism
04/2021
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
04/2021
1Shock
04/2021
1Skin Neoplasms (Skin Cancer)
04/2021
1Wounds and Injuries (Trauma)
04/2021
1IgA Deficiency
04/2021
1Bacterial Pneumonia
04/2021
1Chronic Renal Insufficiency
04/2021
1Acute Kidney Injury (Acute Renal Failure)
04/2021
1Arteriovenous Malformations (Arteriovenous Malformation)
01/2021
1Neuroepithelial Neoplasms (Gliomatosis Cerebri)
01/2020
1Prostatic Neoplasms (Prostate Cancer)
12/2019
1Brain Injuries (Brain Injury)
01/2019
1Chronic Obstructive Pulmonary Disease (COPD)
01/2018
1Li-Fraumeni Syndrome
01/2018
1Ganglioglioma
01/2018
1Epilepsy (Aura)
01/2018

Drug/Important Bio-Agent (IBA)

9Temozolomide (Temodar)FDA LinkGeneric
11/2021 - 08/2009
8Bevacizumab (Avastin)FDA Link
01/2021 - 02/2012
4Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2021
3VaccinesIBA
01/2022 - 01/2020
3Histones (Histone)IBA
08/2021 - 11/2019
3ErbB Receptors (EGF Receptor)IBA
07/2014 - 09/2010
3Erlotinib Hydrochloride (CP 358,774)FDA Link
07/2014 - 09/2010
2Dexamethasone (Maxidex)FDA LinkGeneric
08/2022 - 01/2021
2pembrolizumabIBA
01/2021 - 01/2019
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 07/2014
2Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2020 - 01/2014
2Phosphotransferases (Kinase)IBA
01/2020 - 01/2018
2Pharmaceutical PreparationsIBA
01/2018 - 01/2017
2fluoromisonidazoleIBA
10/2016 - 01/2015
2Biological ProductsIBA
01/2015 - 10/2011
2O(6)-Methylguanine-DNA MethyltransferaseIBA
09/2014 - 08/2009
2Tyrosine Kinase InhibitorsIBA
12/2011 - 09/2010
1GlycosidesIBA
02/2022
1proanthocyanidinIBA
02/2022
1PolyphenolsIBA
02/2022
1Anthocyanins (Anthocyanin)IBA
02/2022
1FlavonoidsIBA
02/2022
1Proteins (Proteins, Gene)FDA Link
02/2022
1poly ICLCIBA
01/2022
1Immunologic Factors (Immunomodulators)IBA
01/2022
1durvalumabIBA
01/2022
1Glutens (Glutelin)IBA
12/2021
1Anti-Bacterial Agents (Antibiotics)IBA
04/2021
1Antiviral Agents (Antivirals)IBA
04/2021
1Sodium ChlorideFDA LinkGeneric
04/2021
1Interleukin-6 (Interleukin 6)IBA
04/2021
1Interleukin-8 (Interleukin 8)IBA
04/2021
1Interleukin-10 (Interleukin 10)IBA
04/2021
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
04/2021
1vorasidenibIBA
01/2021
1Immune Checkpoint InhibitorsIBA
01/2021
1CytokinesIBA
01/2021
1AntigensIBA
01/2021
1B7-H1 AntigenIBA
01/2021
1N 30IBA
01/2021
1Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA
01/2020
1Pyruvic Acid (Pyruvate)IBA
01/2020
12,6-dinitrotoluene (DNT)IBA
01/2020
1Carbon-13IBA
01/2020
1Brefeldin AIBA
12/2019
1InterferonsIBA
01/2019
1palbociclibIBA
11/2018
1RNA (Ribonucleic Acid)IBA
01/2018
116S Ribosomal RNAIBA
01/2018
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2018

Therapy/Procedure

17Therapeutics
10/2022 - 05/2009
10Drug Therapy (Chemotherapy)
11/2021 - 11/2011
7Radiotherapy
11/2021 - 05/2009
5Immunotherapy
01/2022 - 01/2014
2Chemoradiotherapy
01/2020 - 08/2009
2Aftercare (After-Treatment)
05/2019 - 03/2018
1Mechanical Ventilators (Ventilator)
04/2021
1Intravenous Infusions
04/2021
1Extracorporeal Membrane Oxygenation
04/2021
1Resuscitation Orders (Do Not Resuscitate Orders)
04/2021
1Renal Replacement Therapy (Therapies, Renal Replacement)
04/2021
1Combined Modality Therapy
01/2021
1Re-Irradiation
09/2019